NeuroQuant AI: The Breakthrough Brain MRI Technology Now at AMI
Advanced Medical Imaging now offers NeuroQuant — FDA-cleared AI that measures brain structures with precision no human eye can match. A new standard in neurological MRI.
Advanced Medical Imaging is proud to announce NeuroQuant — the industry-leading AI-powered brain MRI analysis platform from Cortechs.ai, now available at our Seminole, FL facility. For patients with neurological conditions — Alzheimer's disease, traumatic brain injury (TBI), epilepsy, multiple sclerosis, and more — this changes what a brain MRI can tell you.
What Is NeuroQuant?
NeuroQuant is an FDA-cleared medical device software that uses artificial intelligence to automatically segment and measure over 40 brain structures from a standard high-resolution MRI scan. In minutes after your scan, it produces a detailed volumetric report showing:
- Exact volumes of the hippocampus, cortex, ventricles, and white matter
- Normative comparison — your measurements plotted against a validated database of thousands of healthy brains matched by age and sex
- Color-coded brain maps highlighting where atrophy or abnormality exceeds expected ranges
- Longitudinal tracking — side-by-side comparison of changes across multiple scans over time
The key insight: the human eye cannot reliably detect a 5–10% reduction in hippocampal volume — the kind of subtle atrophy that can mark early Alzheimer's disease. NeuroQuant can. In studies of chronic TBI patients, NeuroQuant identified atrophy or asymmetry in over 90% of cases, compared to just 12% detected by standard visual assessment alone. That's not a small improvement — that's a different category of capability.
Who Benefits From NeuroQuant?
Alzheimer's Disease and Dementia Evaluation
The hippocampus is one of the first brain regions to atrophy in Alzheimer's disease. NeuroQuant measures hippocampal volume precisely and compares it to an age-matched normative database — detecting shrinkage years before it would be apparent on a conventional read. For patients beginning new disease-modifying therapies (DMTs), NeuroQuant provides a quantitative baseline and objectively tracks treatment response over time. This is increasingly important as new Alzheimer's treatments become available and monitoring becomes part of the standard of care.
Traumatic Brain Injury (TBI)
For patients with a history of concussion, contact sports, military blast exposure, or repeated head trauma, NeuroQuant detects structural changes that traditional MRI misses. Brain atrophy from TBI is often diffuse and subtle — distributed across multiple regions rather than concentrated in one visible lesion. NeuroQuant captures this pattern quantitatively, giving neurologists and physiatrists objective data to guide diagnosis and rehabilitation planning.
Epilepsy
In pre-surgical epilepsy evaluation, identifying which temporal lobe has mesial temporal sclerosis (MTS) is critical for surgical planning. NeuroQuant has been shown to match subspecialist neuroradiologist accuracy for lateralizing MTS — in a fraction of the time, and without requiring a dedicated epilepsy MRI center. For community practices managing complex epilepsy patients, this is a meaningful advance.
Multiple Sclerosis (MS)
NeuroQuant tracks whole-brain atrophy over time — an established MS disease progression biomarker — and measures white matter lesion burden with precision. Serial scans can demonstrate whether a patient is progressing, stable, or responding to therapy. The National Multiple Sclerosis Society recognizes MRI as the cornerstone of MS monitoring.
General Neurology
Any patient with unexplained memory loss, cognitive decline, neuropsychological symptoms, or a neurology-ordered brain MRI may benefit from NeuroQuant post-processing. If your neurologist, psychiatrist, or primary care physician has ordered a brain MRI and is evaluating for cognitive or structural changes, ask about adding NeuroQuant.
NeuroQuant 5.0 — The Latest FDA-Cleared Version
AMI offers NeuroQuant 5.0 — the most advanced release to date. New in this version:
- Susceptibility-sensitive MRI integration — enhanced detection of smaller brain lesions including microbleeds and iron deposits
- Improved brain tumor AI models — automated segmentation and volumetric tracking of brain metastases and meningiomas
- ARIA monitoring — critical for patients on anti-amyloid Alzheimer's therapies, where amyloid-related imaging abnormalities must be tracked closely
This is not a research prototype. NeuroQuant is an FDA-cleared Class II medical device used by thousands of radiologists at leading academic centers and community practices worldwide. As of January 2024, new CPT Category III codes (0865T, 0866T) are active for AI-assisted quantitative brain MRI analysis — an important step toward broader reimbursement coverage.
What to Expect
NeuroQuant runs automatically on your existing brain MRI — no additional scan time, no extra procedures, no additional IV or contrast needed. The standard 3D T1-weighted MRI sequence (already included in most brain MRI protocols) is processed through the NeuroQuant software in the cloud. Results appear as a color-coded volumetric report that your neurologist or referring physician receives alongside the standard radiology read.
The entire process is seamless and invisible to the patient. You simply schedule your brain MRI at AMI, the scan is performed as normal, and your physician receives a richer, more objective report.
Schedule Your Brain MRI at AMI
If you have a brain MRI scheduled — or if your neurologist has recommended one — ask about adding NeuroQuant AI post-processing. We offer same-week appointments, experienced MRI technologists, and board-certified radiologist reads.
Call (727) 398-5999 or schedule online. If you experience claustrophobia, ask about our Open MRI option.
Learn more about how MRI works and what brain MRI detects in our patient education library.
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